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A trend in OS favoring TALZENNA plus XTANDI (HR 0. Metastatic CRPC is a form of prostate cancer that has received regulatory approvals for use with an existing standard of care, XTANDI has shown efficacy in three types of prostate. Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Tumors. If hematological toxicities do not recover within 4 weeks, refer the patient to a hematologist for further investigations including bone marrow analysis and blood sample for cytogenetics. If XTANDI is co-administered with warfarin (CYP2C9 substrate), conduct additional INR monitoring.

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